High-speed HPLC analysis to improve lab analysis productivity began in 1982 with the Shimadzu LC-5A/FLC column. In 2006, the Prominence UFLC/XR column system achieved ultra high-speeds while ensuring repeatability during continuous multi-sample analysis, in addition to maintaining durability and other forms of data stability. Since general HPLC analysis is insufficient with respect to qualitative capabilities, risks related to overlooking impurities that can obscure peaks remain. Mass spectrometers are effective at minimizing these risks. To date, however, a commercial MS capable of reliably providing the kind of sharp peaks obtained with ultra high-speed LC has not been available.

The ultra high-speed LC/MS Prominence UFLC+LCMS-2020 improves the speed and reliability of HPLC analysis, offering dramatic improvements in lab productivity.

By incorporating the following innovative features into the LCMS-2020, the sharp peaks of ultra high-speed LC won't be missed:

• (high-speed positive/negative ionization mode switching)
• (high-speed scan measurements)
• (superior sensitivity and repeatability thanks to newly developed ion optics)

The UFLC/MS, which continues the tradition of high-level data reliability from the well-received ultra high-speed LC Prominence UFLC, has now been released.